Effects of vitamin D receptor gene polymorphism and clinical characteristics on risk of diabetic retinopathy in Han Chinese type 2 diabetes patients.

@article{Zhong2015EffectsOV,
  title={Effects of vitamin D receptor gene polymorphism and clinical characteristics on risk of diabetic retinopathy in Han Chinese type 2 diabetes patients.},
  author={Xing Zhong and Yijun Du and Yuan Lei and Nina Liu and Yanyun Guo and Tianrong Pan},
  journal={Gene},
  year={2015},
  volume={566 2},
  pages={212-6}
}
PURPOSE The purpose of this study was to investigate the association of VDR polymorphism with development of retinopathy in a Han Chinese population with type 2 diabetes mellitus. MATERIALS AND METHODS A total of 204 T2DM patients were subdivided into groups without diabetic retinopathy (NDR, n=110) and those with DR (n=94). VDR rs2228570 (FokI:C>T), rs1544410 (BsmI:G>A), and rs7975232 (Apal:A>C) polymorphism was assayed by polymerase chain reaction-restriction fragment length polymorphism… CONTINUE READING