Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram.

@article{Ohshima2009EffectsOV,
  title={Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram.},
  author={Hiroshi Ohshima and Koji Mizukoshi and Midori Oyobikawa and Katsuo Matsumoto and Hirotsugu Takiwaki and Hiromi Kanto and Masatoshi Itoh},
  journal={Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging},
  year={2009},
  volume={15 2},
  pages={
          214-7
        }
}
BACKGROUND/AIMS The pathogenesis of dark circles of the lower eyelid (DCLE) has been considered to involve stasis and hyperpigmentation of the eyelids. We have already reported that dermal thickness of lower eyelid skin may represent another factor that affects the appearance of DCLE. The aim of this study was to evaluate the efficacy of vitamin C, which is known to increase collagen, on DCLE through a clinical trial. METHODS Fourteen subjects with DCLE applied either 10% sodium ascorbate… CONTINUE READING
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