Effects of vitamin C on airway responsiveness to inhaled histamine in heavy smokers.

@article{Bucca1989EffectsOV,
  title={Effects of vitamin C on airway responsiveness to inhaled histamine in heavy smokers.},
  author={Caterina B Bucca and Giovanni Rolla and E Caria and Walter Arossa and Massimiliano Bugiani},
  journal={The European respiratory journal},
  year={1989},
  volume={2 3},
  pages={229-33}
}
Histamine bronchial threshold, the provocation concentration of histamine causing a 25% fall in maximal expiratory flow at 50% of forced vital capacity from the control value (PC25MEF50), was measured in seven heavy smokers and in seven sex- and age-matched nonsmokers before and one hour after ingestion, double-blind, of vitamin C (2 g) or placebo. Smokers had significantly lower baseline values of serum ascorbate, maximal expiratory flow at 50% of forced vital capacity (MEF50) and PC25MEF50… CONTINUE READING

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