Effects of vitamin A and dexamethasone on capsule collagen metabolism in mouse mammary adenocarcinoma.


It was previously shown that the administration of dexamethasone (Dex) to mice bearing mammary adenocarcinoma caused the collagen content of the tumor capsule to be decreased by 50%, but collagenase and other neutral protease activities of the tumor were the same as in the controls. These events occurred with distinctly increased tumor invasion and… (More)


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