Effects of various vehicles on the penetration of flufenamic acid into human skin.

@article{Wagner2004EffectsOV,
  title={Effects of various vehicles on the penetration of flufenamic acid into human skin.},
  author={Heike Wagner and K L Kostka and Willi Adelhardt and Ulrich F. Sch{\"a}fer},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2004},
  volume={58 1},
  pages={121-9}
}
The effect of various vehicles (polyacrylate gels and wool alcohol ointments) on the penetration of flufenamic acid into excised human skin was investigated. Physico-chemical properties of the formulations were examined and discussed. Penetration data was gathered using two different in vitro test systems: the Saarbruecken penetration model (SB-M) and the Franz diffusion cell (FD-C). With wool alcohol ointments, drug concentration in the formulation was the decisive parameter for drug… CONTINUE READING

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