Effects of various psychotomimetic agents on the EEG and acetylcholine release from the cerebral cortex of brainstem transected cats.

@article{Domino1972EffectsOV,
  title={Effects of various psychotomimetic agents on the EEG and acetylcholine release from the cerebral cortex of brainstem transected cats.},
  author={Edward F. Domino and Alessandro Bartolini},
  journal={Neuropharmacology},
  year={1972},
  volume={11 5},
  pages={
          703-13
        }
}
Abstract The effects of i.v. administration of Δ 9 THC, phencyclidine, the pyrrolidyl and piperidyl isomers of Ditran, and LSD-25 were determined on the spontaneous neocortical EEG and release of acetylcholine (ACh) from the somatosensory cortex of brainstem transected cats. Δ 9 THC was given in doses of 0.5–11 mg kg i.v. to animals with a pretrigeminal midpontine transection. Δ 9 THC produced neocortical high voltage EEG slow waves which were more prominent in the frontal areas of the brain… CONTINUE READING

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