Effects of vanadate on mechanical responses and Na-K pump in vascular smooth muscle.

@article{Ozaki1980EffectsOV,
  title={Effects of vanadate on mechanical responses and Na-K pump in vascular smooth muscle.},
  author={Hiroshi Ozaki and Norimoto Urakawa},
  journal={European journal of pharmacology},
  year={1980},
  volume={68 3},
  pages={339-47}
}
The effects of vanadate on tension and on the Na-K pump in isolated guinea-pig aorta were investigated. Vanadates (NH4VO3 or Na3VO4 . nH2O) (10(-3) M) produced a sustained contraction (about 0.5 g) which was not influenced by phentolamine (10(-6) M). In the absence of external Ca, vanadate and norepinephrine (2 x 10(-6) M) induced a small contraction… CONTINUE READING