Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells.

@article{CoyralCastel2010EffectsOU,
  title={Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells.},
  author={St{\'e}phanie Coyral-Castel and Christelle Ram{\'e} and Alice Fatet and Jo{\"e}lle Dupont},
  journal={Domestic animal endocrinology},
  year={2010},
  volume={38 4},
  pages={
          272-83
        }
}
Previous studies in cattle have shown influences of dietary unsaturated fatty acid (UFA) supplementation on ovarian function. However, it is unclear whether these UFA exert direct or indirect effects on ovarian steroid production or their mechanisms of action. We have recently shown that 5'AMP-activated protein kinase (AMPK) regulates progesterone secretion through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 (MAPK ERK1/2) in rodent granulosa cells. Here, we… CONTINUE READING

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