Effects of unilateral vagotomy on nitric oxide synthase and histamine H3 receptors in the rat dorsal vagal complex.

@article{Zhao1996EffectsOU,
  title={Effects of unilateral vagotomy on nitric oxide synthase and histamine H3 receptors in the rat dorsal vagal complex.},
  author={Xudong Zhao and Kazuhiko Yanai and Yoko Hashimoto and Harry W. M. Steinbusch and Tomoyasu Watanabe},
  journal={Journal of chemical neuroanatomy},
  year={1996},
  volume={11 4},
  pages={221-9}
}
Nitric oxide synthase (NOS) and histamine H3 receptors are both markedly increased by neuronal injuries. To examine whether peripheral axotomy produced differential changes in NOS and H3 receptors, both NOS and H3 receptors were measured in the dorsal vagal complex after unilateral vagotomy. The presence of NOS-positive neurons was examined using both NADPH-diaphorase histochemistry and neuronal NOS-immunohistochemistry in rats vagotomized at the mid-cervical level. NADPH-diaphorase activity… CONTINUE READING