Effects of unilateral motor cortex lesion on ipsilesional hand's reach and grasp performance in monkeys: relationship with recovery in the contralesional hand.

@article{Kaeser2010EffectsOU,
  title={Effects of unilateral motor cortex lesion on ipsilesional hand's reach and grasp performance in monkeys: relationship with recovery in the contralesional hand.},
  author={Melanie J. Kaeser and Alexander F. Wyss and Shahid Bashir and Adjia Hamadjida and Yu Liu and Jocelyne Bloch and J J Brunet and Abderaouf Belhaj-Saif and Eric M. Rouiller},
  journal={Journal of neurophysiology},
  year={2010},
  volume={103 3},
  pages={1630-45}
}
Manual dexterity, a prerogative of primates, is under the control of the corticospinal (CS) tract. Because 90-95% of CS axons decussate, it is assumed that this control is exerted essentially on the contralateral hand. Consistently, unilateral lesion of the hand representation in the motor cortex is followed by a complete loss of dexterity of the contralesional hand. During the months following lesion, spontaneous recovery of manual dexterity takes place to a highly variable extent across… CONTINUE READING
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Interhemispheric interaction after unilateral motor cortex lesion

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