Effects of unilateral labyrinthectomy on GAD, GAT1 and GABA receptor gene expression in the rat vestibular nucleus.

@article{Horii2003EffectsOU,
  title={Effects of unilateral labyrinthectomy on GAD, GAT1 and GABA receptor gene expression in the rat vestibular nucleus.},
  author={Arata Horii and Tadashi Kitahara and Paul F Smith and Cynthia L. Darlington and Chisako Masumura and Takeshi Kubo},
  journal={Neuroreport},
  year={2003},
  volume={14 18},
  pages={2359-63}
}
To elucidate the role of the GABAergic neuronal system in the recovery from peripheral vestibular damage (unilateral labyrinthectomy), we used a real-time quantitative reverse transcription-polymerase chain reaction method to investigate the mRNA expression of GAD65, GAD67, the GABAA receptor alpha1 subunit, the GABAB R1 subunit, and the GABA transporter GAT1, in the vestibular nucleus complex of the rat 6 and 50 h following the lesion GAD65 and GAD67 gene expression were also measured in the… CONTINUE READING
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