Effects of two inhibitors of renin-angiotensin system on attenuation of postoperative remodeling after left ventricular aneurysm repair in rats.

@article{Nomoto2003EffectsOT,
  title={Effects of two inhibitors of renin-angiotensin system on attenuation of postoperative remodeling after left ventricular aneurysm repair in rats.},
  author={Takuya Nomoto and Takeshi Nishina and Hiroshi Tsuneyoshi and Senri Miwa and Kazunobu Nishimura and Masashi Komeda},
  journal={Journal of cardiac surgery},
  year={2003},
  volume={18 Suppl 2},
  pages={S61-8}
}
We reported that the initial beneficial effects of left ventricular repair (LVR) surgery for LV aneurysm after myocardial infarction (MI) did not persist because of postoperative LV remodeling in a rat model. The renin-angiotensin system (RAS) plays an important role in postinfarction LV remodeling. Inhibition of RAS may be useful to preserve LV function by… CONTINUE READING