Effects of tryptophan loading on human cognition, mood, and sleep.

  title={Effects of tryptophan loading on human cognition, mood, and sleep.},
  author={Beata Y. Silber and Jeroen Schmitt},
  journal={Neuroscience and biobehavioral reviews},
  volume={34 3},
Modulating central serotonergic function by acute tryptophan depletion (ATD) has provided the fundamental insights into which cognitive functions are influenced by serotonin. It may be expected that serotonergic stimulation by tryptophan (Trp) loading could evoke beneficial behavioural changes that mirror those of ATD. The current review examines the evidence for such effects, notably those on cognition, mood and sleep. Reports vary considerably across different cognitive domains, study designs… CONTINUE READING
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