Effects of tryptophan depletion in drug-free adults with autistic disorder.

  title={Effects of tryptophan depletion in drug-free adults with autistic disorder.},
  author={Christopher J. McDougle and Stephanie Naylor and Donald J. Cohen and George K. Aghajanian and George R. Heninger and Lawrence H. Price},
  journal={Archives of general psychiatry},
  volume={53 11},
BACKGROUND The primary objective of this study was to investigate the behavioral and biochemical responses to acute tryptophan depletion in drug-free adult patients with autistic disorder. METHODS Twenty drug-free adults with autistic disorder (16 men and 4 women) (mean [+/- SD] age, 30.5 +/- 8.5 years) underwent short-term tryptophan depletion in a double-blind, placebo-controlled, randomized crossover design. Patients received a 24-hour, low-tryptophan diet followed the next morning by an… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 91 extracted citations

Similar Papers

Loading similar papers…