Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae.

@article{Liu2013EffectsOT,
  title={Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae.},
  author={Chunsheng Liu and Qiangwei Wang and Kang Liang and Jingfu Liu and Bingsheng Zhou and Xiaowei Zhang and Hongling Liu and John Paul Giesy and Hongxia Yu},
  journal={Aquatic toxicology},
  year={2013},
  volume={128-129},
  pages={147-57}
}
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) and triphenyl phosphate (TPP) are frequently detected in biota, including fish. However, knowledge of the toxicological and molecular effects of these currently used flame retardants is limited. In the present study, an in vivo screening approach was developed to evaluate effects of TDCPP and TPP on developmental endpoints and receptor-associated expression of mRNA in zebrafish embryos/larvae. Exposure to TDCPP or TPP resulted in significantly… CONTINUE READING

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