Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion.

@article{Sucu2002EffectsOT,
  title={Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion.},
  author={Nehir Sucu and Ali Unlu and Lulufer Tamer and Barlas Naim Aytaçoğlu and Banu Coşkun and Ramazan Bilgin and Bahadir Ercan and Ali Gul and Murat Dikmengil and Uğur Atik},
  journal={Pharmacological research},
  year={2002},
  volume={46 4},
  pages={345-9}
}
The objective of this study was to investigate the effects of trimetazidine (TMZ) on tissue damage in kidney after hindlimb ischemia-reperfusion (I/R), by assessing blood biochemical assay and histopathological analysis. Adult male Wistar rats were divided into two groups. TMZ 10 mg kg(-1)day(-1) was administrated twice a day for 10 days to the treatment group (group T, n=10). Sham group was given only 5% gum arabic (group S, n=10). On 11th day of treatment, 8h I/R period was performed on right… CONTINUE READING