Effects of trimetazidine and selenium on high-frequency fatigue in isolated rat diaphragm muscle.

Trimetazidine (TMZ), which has been used in numerous experimental studies, is applied nowadays with the aim of reducing myocardial ischemia. The aim of this study was to determine the prefatigue and postfatigue contractile characteristics associated with the relationship between the force and frequency of contraction in muscle. The study was conducted using… CONTINUE READING