Effects of tricyclic antidepressants on mechanosensitive pelvic nerve afferent fibers innervating the rat colon

@article{Su1998EffectsOT,
  title={Effects of tricyclic antidepressants on mechanosensitive pelvic nerve afferent fibers innervating the rat colon},
  author={Xin Su and Gerald F. Gebhart},
  journal={Pain},
  year={1998},
  volume={76},
  pages={105-114}
}
The aim of this study was to examine the effects of tricyclic antidepressants on responses of mechanosensitive afferent fibers innervating the rat colon. A total of 53 fibers in the decentralized S1 dorsal root were studied. The effects of the non-specific monoamine reuptake inhibitor imipramine (IMI), the noradrenaline reuptake inhibitor desipramine (DES), and the serotonin reuptake inhibitor clomipramine (CLO) were tested on responses of 22 mechanosensitive afferent fibers to noxious… CONTINUE READING

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