Effects of trauma on immune cell function: impairment of intracellular calcium signaling.

@article{Hoyt1994EffectsOT,
  title={Effects of trauma on immune cell function: impairment of intracellular calcium signaling.},
  author={David Butler Hoyt and Wolfgang G. Junger and William H. Loomis and Forrest C. Liu},
  journal={Shock},
  year={1994},
  volume={2 1},
  pages={
          23-8
        }
}
Immunosuppression following injury influences infectious morbidity and mortality. Impaired T-cell activation conceding to inadequate antigen recognition contributes to this immunosuppression. Successful activation and proliferation of T-cells requires precisely specified levels of intracellular calcium thresholds and peak signals. The purpose of this study was to evaluate intracellular calcium signaling following injury. Hospitalized blunt and penetrating trauma patients in a Level 1 Trauma… CONTINUE READING
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