Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder

@article{Yehuda2004EffectsOT,
  title={Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder},
  author={Rachel Yehuda and Sarah L. Halligan and Julia A. Golier and Robert A Grossman and Linda M. Bierer},
  journal={Psychoneuroendocrinology},
  year={2004},
  volume={29},
  pages={389-404}
}

Basal and suppressed salivary cortisol in female Vietnam nurse veterans with and without PTSD

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The data support earlier studies showing that HPA abnormalities in PTSD are different from those seen in depression and suggest that the low-dose dexamethasone suppression test may be a potentially useful tool for differentiating the two syndromes and further exploring differences in their pathophysiology.

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TLDR
A possible role of defensive organization as a basis for the low, constricted cortisol levels in PTSD and paranoid schizophrenic patients is suggested and the possible usefulness of hormonal criteria as an adjunct to the clinical diagnosis of PTSD is suggested.

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TLDR
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TLDR
A physiological adaptation of the hypothalamic-pituitary- adrenal axis to chronic stress is suggested in posttraumatic stress disorder (PTSD).