Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder

@article{Yehuda2004EffectsOT,
  title={Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder},
  author={Rachel Yehuda and Sarah L Halligan and Julia A. Golier and Robert A Grossman and Linda M. Bierer},
  journal={Psychoneuroendocrinology},
  year={2004},
  volume={29},
  pages={389-404}
}
OBJECTIVE To evaluate cortisol suppression following 0.5 mg of dexamethasone (DEX) in trauma survivors (N=52) with posttraumatic stress disorder (PTSD), major depressive disorder (MDD), both, or neither disorder, and in subjects never exposed to trauma (N=10), in order to examine interactions between diagnosis and trauma history on cortisol negative feedback inhibition. METHOD Lifetime trauma exposure and psychiatric diagnoses were assessed and blood samples were obtained at 8:00 a.m. for the… Expand
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