Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder

@article{Yehuda2004EffectsOT,
  title={Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder},
  author={R. Yehuda and S. Halligan and J. Golier and R. Grossman and L. Bierer},
  journal={Psychoneuroendocrinology},
  year={2004},
  volume={29},
  pages={389-404}
}
  • R. Yehuda, S. Halligan, +2 authors L. Bierer
  • Published 2004
  • Medicine, Psychology
  • Psychoneuroendocrinology
  • OBJECTIVE To evaluate cortisol suppression following 0.5 mg of dexamethasone (DEX) in trauma survivors (N=52) with posttraumatic stress disorder (PTSD), major depressive disorder (MDD), both, or neither disorder, and in subjects never exposed to trauma (N=10), in order to examine interactions between diagnosis and trauma history on cortisol negative feedback inhibition. METHOD Lifetime trauma exposure and psychiatric diagnoses were assessed and blood samples were obtained at 8:00 a.m. for the… CONTINUE READING
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    References

    SHOWING 1-10 OF 37 REFERENCES
    Enhanced Dexamethasone Suppression of Plasma Cortisol in Adult Women Traumatized by Childhood Sexual Abuse
    • 330
    Prospective study of posttraumatic stress disorder and depression following trauma.
    • 908
    • PDF
    Urinary Free-Cortisol Levels in Posttraumatic Stress Disorder Patients
    • 404
    The potential role of hypocortisolism in the pathophysiology of PTSD and psoriasis.
    • 80
    Low Urinary Cortisol Excretion in Patients with Posttraumatic Stress Disorder
    • 496