Effects of transferrin on aromatase activity in porcine granulosa cells in vitro.

@article{Durlej2008EffectsOT,
  title={Effects of transferrin on aromatase activity in porcine granulosa cells in vitro.},
  author={Małgorzata Durlej and Małgorzata Duda and Katarzyna Knapczyk and Maria Słomczyńska},
  journal={Folia histochemica et cytobiologica},
  year={2008},
  volume={46 4},
  pages={423-8}
}
Proliferating cells have an absolute requirement for iron, which is delivered by transferrin with subsequent intracellular transport via the transferrin receptor. Recent studies have reported that transferrin plays a crucial role in the local regulation of ovarian function, apart from its iron-binding characteristic. Therefore, the present study was undertaken to explore the possible role of transferrin in porcine granulosa cells function by examining its influence on aromatase activity, the… CONTINUE READING