• Corpus ID: 92729925

Effects of transcranial light on molecules regulating circadian rhythm

@inproceedings{Flyktman2018EffectsOT,
  title={Effects of transcranial light on molecules regulating circadian rhythm},
  author={Antti Flyktman},
  year={2018}
}
Light acts as the most important regulating and entraining factor of the mammalian circadian rhythm. This rhythm has evolved to set phases, in which different physiological and behavioral events occur at the right time of the day to synchronize the organism. The mechanism of light transduction via eyes to the brain and its effects on circadian rhythmicity is well known. Yet, it has also been shown that light is able to penetrate the skull bone directly, but it is still unknown, whether… 
6 Citations

Figures and Tables from this paper

Decadal time-scale vegetation changes at high latitudes : responses to climatic and non-climatic drivers
Boreal and arctic plant communities are responding to anthropogenic climate change that has been exceptionally rapid during the recent decades. General responses include increased productivity, range
Ecology of lawbreaking : effects of poaching on legally harvested wolf populations in human-dominated landscapes
Illegal killing of wolves (hereinafter ’wolf poaching’) in human-inhabited areas, where wolves are also legally harvested is a special case of wildlife crime. This doctoral thesis examines wolf
On regularized estimation methods for precision and covariance matrix and statistical network inference
TLDR
It is illustrated how community detection can be a promising tool in population structure and admixture exploration of genetic data and how the precision matrix estimator introduced in Article I can be used in graphical model selection via a multiple hypothesis testing procedure.
The effects of confirmation bias and time pressure in software testing
TLDR
Time pressure emerged as a major antecedent to confirmation bias in the grounded theory and testers should develop self-awareness of confirmation bias and improve their perception of performance to improve their actual testing.
Application of persuasive systems design for adopting green information systems and technologies
TLDR
This dissertation focuses on finding out how to encourage people to adopt and continue using mobile applications designed to assist with acquiring sustainable habits and behaviors and reveals a high potential of the PSD model to become a vehicle for enhancement of the existing Green IS/IT.
Requirements fixation: the effect of specification formality on design creativity
TLDR
The results of this dissertation suggest that more formal and structured presentations of Desiderata cause requirements fixation, the tendency to attribute undue confidence and importance to desiderata presented as formal requirements statements---that affects design creativity, and thus undermines software engineering success.

References

SHOWING 1-10 OF 162 REFERENCES
Peripheral Circadian Oscillators in Mammals: Time and Food
TLDR
Experimental systems by which the identification of physiologically relevant agents used by the SCN to synchronize peripheral clocks will clearly be an arduous undertaking are felt to be at hand.
Melanopsin resets circadian rhythms in cells by inducing clock gene Period1
TLDR
Per1 induction was measured by reporter signal assay in Per2∷luc and Per1∷GFP fibroblast cell at the input process of circadian rhythms and it was found that signals transduction leads to Per1 expression being induced immediately after a light pulse.
Effect of Light on Human Circadian Physiology.
Resetting central and peripheral circadian oscillators in transgenic rats.
TLDR
It is hypothesize that a self-sustained circadian pacemaker in the SCN entrains circadian oscillators in the periphery to maintain adaptive phase control, which is temporarily lost following large, abrupt shifts in the environmental light cycle.
Dim Light at Night Disrupts Molecular Circadian Rhythms and Increases Body Weight
TLDR
Evidence is provided that mild changes in environmental lighting can alter circadian and metabolic function and detailed analysis of temporal changes induced by nighttime light exposure may provide insight into the onset and progression of obesity and metabolic syndrome, as well as other disorders involving sleep and circadian rhythm disruption.
The Circadian Response of Intrinsically Photosensitive Retinal Ganglion Cells
TLDR
Out Outer retinal photoreceptor contributions to the inner retinal ipRGC driven post-illumination pupil response also show circadian variation whereas direct outer retinal cone inputs to the pupil light reflex do not, indicating that intrinsically photosensitive retinal ganglion cells mediate this circadian variation.
No Evidence for Extraocular Photoreceptors in the Circadian System of the Syrian Hamster
TLDR
It is concluded that extraocular phototransduction is not capable of shifting the phase of the hamster's locomotor activity rhythm or of suppressing pineal melatonin synthesis.
Extraocular circadian phototransduction in humans.
TLDR
These findings challenge the belief that mammals are incapable of extraretinal circadian phototransduction and have implications for the development of more effective treatments for sleep and circadian rhythm disorders.
Endogenous Regulation of Serotonin Release in the Hamster Suprachiasmatic Nucleus
TLDR
Results show that the daily rhythm in output of 5-HT in the SCN is generated endogenously, and that behavioral state can strongly influence serotonergic activity in the circadian clock in a phase-dependent manner.
...
1
2
3
4
5
...