Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system.

@article{Awad2007EffectsOT,
  title={Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system.},
  author={Rosalie Awad and Dylan Levac and Paulina Cybulska and Zul Merali and Vance L. Trudeau and John T Arnason},
  journal={Canadian journal of physiology and pharmacology},
  year={2007},
  volume={85 9},
  pages={933-42}
}
In Canada, the use of botanical natural health products (NHPs) for anxiety disorders is on the rise, and a critical evaluation of their safety and efficacy is required. The purpose of this study was to determine whether commercially available botanicals directly affect the primary brain enzymes responsible for gamma-aminobutyric acid (GABA) metabolism. Anxiolytic plants may interact with either glutamic acid decarboxylase (GAD) or GABA transaminase (GABA-T) and ultimately influence brain GABA… CONTINUE READING

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