Effects of topical latanoprost on optic nerve head circulation in rabbits, monkeys, and humans.

  title={Effects of topical latanoprost on optic nerve head circulation in rabbits, monkeys, and humans.},
  author={Kiyoshi Ishii and Atsuo Tomidokoro and Miyuki Nagahara and Yasuhiro Tamaki and Mikiko Kanno and Yasuhiro Fukaya and Makoto Araie},
  journal={Investigative ophthalmology & visual science},
  volume={42 12},
PURPOSE To evaluate the effect of topically administrated latanoprost on optic nerve head (ONH) circulation in Dutch rabbits, cynomolgus monkeys, and normal humans. METHODS The ONH tissue blood velocity (NB(ONH)) was determined using the laser speckle method. Latanoprost (0.005%, 30 microl) was instilled into one eye, and vehicle into the other eye as a control. In rabbits, NB(ONH) was measured for 90 minutes after a single instillation and before and after a 7-day once-daily instillation… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 23 extracted citations

Ocular Blood Flow and Influencing Factors for Glaucoma.

Asia-Pacific journal of ophthalmology • 2016
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 44 references

Effects of 0.005% latanoprost on optic nerve head and peripapillary retinal blood flow.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde • 1999

flow in normal tension glaucoma

Sapeth GL. Minckler DS

Anatomy, physiology, and biochemistry of the rabbit

C Kozuma, W Macklin, LM Cumminus, R. Mauer
Weisbroth SH, Flatt RE, Kraus AL, eds. The Biology of the Laboratory Rabbit • 1998

Effects of prostaglandin E2, F2alpha, and latanoprost acid on isolated ocular blood vessels in vitro.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • 1998

Similar Papers

Loading similar papers…