Effects of tobacco smoke on the secretion of interleukin-1beta, tumor necrosis factor-alpha, and transforming growth factor-beta from peripheral blood mononuclear cells.

@article{Ryder2002EffectsOT,
  title={Effects of tobacco smoke on the secretion of interleukin-1beta, tumor necrosis factor-alpha, and transforming growth factor-beta from peripheral blood mononuclear cells.},
  author={Mark I. Ryder and Mehrnoosh Saghizadeh and Yan-rui Ding and Nhat Bich Thi Nguyen and Aubrey Soskolne},
  journal={Oral microbiology and immunology},
  year={2002},
  volume={17 6},
  pages={331-6}
}
Alterations of the host response caused by short-term exposure to high levels of smoke during the act of smoking (acute smoke exposure) as well as long-term exposure to lower levels of tobacco substances in the bloodstream of smokers (chronic smoke exposure) may play a role in the pathogenesis of periodontal diseases in smokers. In this study, we examined the secretion of three cytokines [interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha, and transforming growth factor (TGF)-beta] from… CONTINUE READING

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