Effects of thyroid hormones on the heart.

  title={Effects of thyroid hormones on the heart.},
  author={Hernando Vargas-Uricoechea and Anilsa Bonelo-Perdomo and Carlos H. Sierra-Torres},
  journal={Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis},
  volume={26 6},
Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormone deficiencies, as well as excesses, are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics. Thyroid hormones upregulate the expression of the sarcoplasmic reticulum calcium-activated ATPase and downregulate the expression of phospholamban. Overall, hyperthyroidism is characterized by an increase in resting… CONTINUE READING


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