Effects of the type of embolization particles on carboplatin concentration in liver tumors after transcatheter arterial chemoembolization in a rabbit model of liver cancer.

@article{Hong2005EffectsOT,
  title={Effects of the type of embolization particles on carboplatin concentration in liver tumors after transcatheter arterial chemoembolization in a rabbit model of liver cancer.},
  author={K. K. Hong and Hisham Kobeiter and Christos S Georgiades and Michael S. Torbenson and Jean Francois H Geschwind},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={2005},
  volume={16 12},
  pages={1711-7}
}
PURPOSE To study the effect of particle type used during transarterial hepatic chemoembolization (TACE) on carboplatin concentration after TACE in an animal model of liver cancer (VX2) and to determine the concentration of carboplatin within tumor, liver, and plasma. MATERIALS AND METHODS The VX2 tumors were grown in the livers of 23 rabbits. Carboplatin (5 mg/kg) was selected because of its known potency against VX2 tumor. Group 1 was treated with TACE with tris-acryl gelatin microspheres… CONTINUE READING

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