Effects of the systemic administration of kainic acid and NMDA on exploratory activity in rats

@article{GimnezLlort1995EffectsOT,
  title={Effects of the systemic administration of kainic acid and NMDA on exploratory activity in rats},
  author={Lydia Gim{\'e}nez-Llort and Sergi Ferr{\'e} and E V{\'a}squez Mart{\'i}nez},
  journal={Pharmacology Biochemistry and Behavior},
  year={1995},
  volume={51},
  pages={205-210}
}
In spite of growing evidence for the involvement of the glutamatergic system in mammal's locomotion, studies on behavioral effects induced by the systemic administration of excitatory amino acids not associated to convulsions are lacking. In the present work, the effect of one single systemic administration of kainic acid (KA) (9 mg/kg, IP) or NMDA (100 mg/kg, IP) on exploratory activity in the rat during 6 consecutive days was studied. Separation of exploratory activity in fast (FM) and slow… CONTINUE READING
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