Effects of the shape of distribution of mutant effect in nearly neutral mutation models

  title={Effects of the shape of distribution of mutant effect in nearly neutral mutation models},
  author={Hidenori Tachida},
  journal={Journal of Genetics},
Models of the theory of nearly neutral mutation incorporate a continuous distribution of mutation effects in contrast to the theory of purely neutral mutation which allows no mutations with intermediate effects. Previous studies of one such model, namely the house-of-cards mutation model, assumed normal distribution of mutation effect. Here I study the house-of-cards mutation model in random-mating finite populations using the weak-mutation approximation, paying attention to the effects of the… CONTINUE READING
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