Effects of the prone position on respiratory mechanics and gas exchange during acute lung injury.

@article{Pelosi1998EffectsOT,
  title={Effects of the prone position on respiratory mechanics and gas exchange during acute lung injury.},
  author={Paolo Pelosi and Daniela Tubiolo and D. Mascheroni and Pierluigi Vicardi and Stefania Crotti and Franco Valenza and Luciano Gattinoni},
  journal={American journal of respiratory and critical care medicine},
  year={1998},
  volume={157 2},
  pages={
          387-93
        }
}
We studied 16 patients with acute lung injury receiving volume-controlled ventilation to assess the relationships between gas exchange and respiratory mechanics before, during, and after 2 h in the prone position. We measured the end-expiratory lung volume (EELV, helium dilution), the total respiratory system (Cst,rs), the lung (Cst,L) and the thoracoabdominal cage (Cst,w) compliances (end-inspiratory occlusion technique and esophageal balloon), the hemodynamics, and gas exchange. In the prone… 
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Respiratory and haemodynamic effects of the prone position at two different levels of PEEP in a canine acute lung injury model.
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The prone position augmented the effect of relatively low positive end-expiratory pressure on oxygenation, and attenuated the haemodynamic impairment of relatively high positive end of-expiration pressure in a canine acute lung injury model.
Sigh in supine and prone position during acute respiratory distress syndrome.
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It is concluded that adding a recruitment maneuver such as cyclical sighs during ventilation in the prone position may provide optimal lung recruitment in the early stage of ARDS.
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The prone position only resulted in improved oxygenation and respiratory mechanics when combined with PEEP = 5 cmH(2)O, and the prone position did not cause hemodynamic compromise with or without PEP = 5cmH( 2)O.
Effects of Prone Positioning on Transpulmonary Pressures and End-expiratory Volumes in Patients without Lung Disease
TLDR
End-expirationatory esophageal pressure decreases, and end-expiratory transpulmonary pressure and expiratory reserve volume increase, when patients are moved from supine to prone position, which may be one mechanism for the observed clinical benefit with prone positioning.
Prone Position in Artificially Ventilated Chronic Obstructive Pulmonary Disease Patients Assessment of Lung Mechani
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Pone position showed significant decrease in plateau pressure and increase in static compliance, it also improves oxygenation and CO2 wash relative to supine position and lasts for at least one hour after turning the patients to the supine positions.
Prone Position Improves Lung Mechanical Behavior and Enhances Gas Exchange Efficiency in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
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Pronation of mechanically ventilated COPD patients exhibits applicability and effectiveness and improves oxygenation and sigh-L mechanics versus semirecumbent (“gold standard”) positioning and certain pronation-related benefits versus preprone-supine positioning are maintained in the postprone supine position.
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It is concluded that the respiratory mechanics in children correlated closely with body size and showed important differences between the supine and lateral positions.
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In severe chronic bronchitis, prone positioning reduces airway resistance and dynamic hyperinflation and benefits were reversed in SRPP.
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References

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TLDR
It is concluded that, in anesthetized and paralyzed obese subjects, the prone position improves pulmonary function, increasing FRC, lung compliance, and oxygenation.
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TLDR
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TLDR
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TLDR
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