Effects of the proapoptotic regulator Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 on the chemosensitivity of human colon cancer cell lines.

Abstract

In the clinical setting, drug resistance remains a significant obstacle for successful chemotherapy. Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 (BNIP3) is a proapoptotic member of the Bcl-2 family. To address its potential as a therapeutic target for chemosensitisation, this study investigated the effect of BNIP3 expression on chemosensitivity and… (More)

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@article{Wang2012EffectsOT, title={Effects of the proapoptotic regulator Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 on the chemosensitivity of human colon cancer cell lines.}, author={Zi Wang and Chunmei Huang and Jianshuang Zeng and Qian Deng and Hui Zeng and Zhen Hua Liu and Xingchen Peng and Feng Bi and Qiulin Tang and Zhiping Li}, journal={Oncology letters}, year={2012}, volume={4 6}, pages={1195-1202} }