Effects of the physico-chemical nature of two biomimetic crystals on the innate immune response.

@article{Ramesh2007EffectsOT,
  title={Effects of the physico-chemical nature of two biomimetic crystals on the innate immune response.},
  author={Manish Ramesh and Laura F Turner and Rajwardhan Yadav and Thiruchandurai V. Rajan and Anthony T. Vella and Liisa Kuhn},
  journal={International immunopharmacology},
  year={2007},
  volume={7 13},
  pages={1617-29}
}
The influence of the physico-chemical features of particulates made of calcium phosphate (hydroxyapatite, HAP) crystals, or monosodium urate monohydrate (MSUM) crystals, on the innate immune response was investigated in mice after intraperitoneal injections. The phenotype and activation status of harvested peritoneal cells from C57BL/6 mice was determined by flow cytometry analysis at 24, 48 and 72 h after particulate injections and compared to a known adjuvant, aluminum phosphate (ALP). A… CONTINUE READING
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