Effects of the monoclonal antibody against porcine 40 kDa adipocyte-specific plasma membrane protein on adipocytes and carcass composition.

@article{Gao2007EffectsOT,
  title={Effects of the monoclonal antibody against porcine 40 kDa adipocyte-specific plasma membrane protein on adipocytes and carcass composition.},
  author={Shizheng Gao and Changrong Ge and Xiaoying Zhang and Yong-gang Liu},
  journal={Acta biochimica et biophysica Sinica},
  year={2007},
  volume={39 7},
  pages={490-8}
}
The effects of the mouse monoclonal antibody against 40 kDa adipocyte-specific plasma membrane protein on porcine adipocytes and carcass composition were investigated in vitro and in vivo. Results revealed that the in vitro complement-mediated cytotoxicity of this monoclonal antibody can lead to adipocyte lysis, remarkable reduction of adipocyte lipid accumulation (P<0.01), and significant decrease of well-differentiated fat cells (P<0.01). Treatment of adipocytes with this antibody alone in… CONTINUE READING