Effects of the lantibiotic mersacidin on the morphology of staphylococci.

  title={Effects of the lantibiotic mersacidin on the morphology of staphylococci.},
  author={Elvira Molitor and C Kluczny and Heike Br{\"o}tz and Gabriele Bierbaum and Rachael Jack and Hans Georg Sahl},
  journal={Zentralblatt fur Bakteriologie : international journal of medical microbiology},
  volume={284 2-3},
Mersacidin is a lanthionine-containing peptide antibiotic (lantibiotic), able to inhibit the growth of a number of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) in a manner similar to, but distinct from, vancomycin. In order to further understand the mode of action of this lantibiotic, Staphylococcus simulans 22 cells were treated either with the antibiotics penicillin, tunicamycin or vancomycin or with mersacidin and then compared with untreated cells… CONTINUE READING