Effects of the flavonoids extracted from Spergularia purpurea Pers. on arterial blood pressure and renal function in normal and hypertensive rats.

@article{Jouad2001EffectsOT,
  title={Effects of the flavonoids extracted from Spergularia purpurea Pers. on arterial blood pressure and renal function in normal and hypertensive rats.},
  author={Hassan Jouad and Marie Aleth Lacaille-Dubois and Badi{\^a}a Lyoussi and Mohamed Eddouks},
  journal={Journal of ethnopharmacology},
  year={2001},
  volume={76 2},
  pages={
          159-63
        }
}
The antihypertensive and diuretic effects of the flavonoids extracted from Spergularia purpurea Pers. (SP) were studied both in normotensive (NTR) and spontaneously hypertensive conscious rats (SHR). Daily oral administration of the flavonoid mixture (5 mg/kg for 1 week) exhibited a significant decrease in blood pressure with variation coefficient (Delta) of 20 in SHR rats and 11 in NTR rats. The systolic and diastolic blood pressure decreased significantly and respectively with 17 and 24% in… CONTINUE READING

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