Effects of the ethylacetate extract of Orostachys japonicus on induction of apoptosis through the p53-mediated signaling pathway in human gastric cancer cells.

@article{Ryu2012EffectsOT,
  title={Effects of the ethylacetate extract of Orostachys japonicus on induction of apoptosis through the p53-mediated signaling pathway in human gastric cancer cells.},
  author={Deok-Seon Ryu and Hyeong-Seon Lee and Gyeong-Seon Lee and Dong-Seok Lee},
  journal={Biological & pharmaceutical bulletin},
  year={2012},
  volume={35 5},
  pages={660-5}
}
Cancer rates are increasing dramatically, and there is currently a strong emphasis on identifying biologically active substances with anti-cancer activity from traditional herbs, as these are thought to have less adverse side-effects than conventional chemotherapy. Here, we examined the effects of extracts of Orostachys japonicus A. BERGER (O. japonicus) on cancer cell proliferation and apoptosis, and investigated the underlying signaling pathways. Dried powdered O. japonicus was extracted with… CONTINUE READING

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