Effects of the dopamine agonist piribedil on prefrontal temporal cortical network function in normal aging as assessed by verbal fluency

@article{Gierski2007EffectsOT,
  title={Effects of the dopamine agonist piribedil on prefrontal temporal cortical network function in normal aging as assessed by verbal fluency},
  author={Fabien Gierski and Charles Siegfried Peretti and A. M. Ergis},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2007},
  volume={31},
  pages={262-268}
}

Figures and Tables from this paper

Substantia Nigra Integrity Correlates with Sequential Working Memory in Parkinson's Disease
TLDR
It is demonstrated that damage to the SN correlates with basal ganglia dysfunction and poor sequencing performance in Parkinson's disease patients, and suggested that the SN may affect sequencing performance by regulating the task-dependent caudate activation in PD patients.
Motor control and aging: Links to age-related brain structural, functional, and biochemical effects
Piribedil for the Treatment of Motor and Non-motor Symptoms of Parkinson Disease
TLDR
Piribedil was considered in the last Movement Disorder Society Evidence-Based Medicine review as “efficacious” and “clinically useful” for the symptomatic treatment of PD, either as monotherapy or in conjunction with levodopa, in non-fluctuating early PD patients.
Influence of the Nonergot Dopamine Agonist Piribedil on Vigilance in Patients With Parkinson Disease and Excessive Daytime Sleepiness (PiViCog-PD): An 11-Week Randomized Comparison Trial Against Pramipexole and Ropinirole
TLDR
This study shows that switching from pramipexole or ropinirole to piribedil has no effect on the reaction time of the TAP subtest vigilance but upholds the same therapeutic motor effect and reduces daytime sleepiness to a clinically relevant degree in patients with excessive daytimeSleepiness.
Role of reward and punishment in motor learning in health and after stroke
TLDR
This thesis investigates the effects of reward and punishment feedback on adaptive motor learning, in both healthy subjects and stroke survivors, and investigates the role of dopamine in error-based motor learning under reward or punishment in healthy young subjects.
Cognition-Enhancing Drugs and Their Appropriateness for Aviation and Ground Troops: A Meta-Analysis
TLDR
A meta-analysis of the 3 studies that met all inclusion criteria revealed a relatively weak pooled effect of modafinil on some aspects of cognitive performance in normal, rested adults, suggesting a large literature gap evaluating the short and long term effects of these drugs in healthy adults.
Visuomotor binding in older adults
...
1
2
...

References

SHOWING 1-10 OF 66 REFERENCES
Effects of ageing on prefrontal temporal cortical network function in healthy volunteers as assessed by COWA An exploratory survey
Psychomotor and cognitive effects of piribedil, a dopamine agonist, in young healthy volunteers
TLDR
It is concluded that a single intravenous perfusion of piribedil 3 mg improves alertness and the information processing speed within the central nervous system, in healthy volunteers.
Effects of bromocriptine on human subjects depend on working memory capacity
TLDR
It is found that the effect of bromocriptine on young normal subjects depended on the subjects' working memory capacity, and this results demonstrate an empirical link between a dopamine-mediated working memory system and higher cognitive function in humans.
Opposing roles for dopamine and serotonin in the modulation of human spatial working memory functions.
TLDR
The findings suggest that monoaminergic neurotransmitters (DA and 5HT) may interact within cortical networks to modulate the expression of specific cognitive behaviors, particularly effortful processes associated with goal-directed activity.
Component analysis of verbal fluency in patients with schizophrenia.
TLDR
The findings of impaired performance for both aspects of fluency, differences between subtypes, and the failure to completely discriminate patients with schizophrenia from controls indicate that there is not a single marker of the disease, at least among these fluency variables.
Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals.
TLDR
Age-related decreases in brain dopamine activity are associated with a decline in motor function and may also contribute to impaired performance on tasks that involve frontal brain regions, including measures of abstraction and mental flexibility.
Age-related cognitive deficits mediated by changes in the striatal dopamine system.
TLDR
D(2) receptor binding is a more important factor than chronological age in accounting for variation in cognitive performance across the adult lifespan, and changes in dopamine neurotransmission play an important role in aging-related cognitive decline.
...
1
2
3
4
5
...