Effects of the cyclopeptide mycotoxin destruxin A on the Malpighian tubules of Rhodnius prolixus (Stål).

@article{RuzSnchez2010EffectsOT,
  title={Effects of the cyclopeptide mycotoxin destruxin A on the Malpighian tubules of Rhodnius prolixus (St{\aa}l).},
  author={Esa{\'u} Ru{\'i}z-S{\'a}nchez and Ian Orchard and Angela B. Lange},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2010},
  volume={55 6},
  pages={1162-70}
}
The production of peptide toxins by entomopathogenic fungi during the infection process plays critical roles in pathogenesis. To gain insight into the mechanism of action of these mycotoxins on insect internal organs, we have evaluated the effects of destruxin A, a cyclic peptide produced by Metarhizium anispliae, on Rhodnius prolixus Malpighian tubules measuring fluid secretion rate, transepithelial electrical potential (TEP), pH and ion composition of secreted fluid, and ATP content… CONTINUE READING

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To gain insight into the mechanism of action of these mycotoxins on insect internal organs , we have evaluated the effects of destruxin A , a cyclic peptide produced by Metarhizium anispliae , on Rhodnius prolixus Malpighian tubules measuring fluid secretion rate , transepithelial electrical potential ( TEP ) , pH and ion composition of secreted fluid , and ATP content .
To gain insight into the mechanism of action of these mycotoxins on insect internal organs , we have evaluated the effects of destruxin A , a cyclic peptide produced by Metarhizium anispliae , on Rhodnius prolixus Malpighian tubules measuring fluid secretion rate , transepithelial electrical potential ( TEP ) , pH and ion composition of secreted fluid , and ATP content .
To gain insight into the mechanism of action of these mycotoxins on insect internal organs , we have evaluated the effects of destruxin A , a cyclic peptide produced by Metarhizium anispliae , on Rhodnius prolixus Malpighian tubules measuring fluid secretion rate , transepithelial electrical potential ( TEP ) , pH and ion composition of secreted fluid , and ATP content .
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