Effects of the cell wall of Kluyveromyces marxianus YIT 8292 on the plasma cholesterol and fecal sterol excretion in rats fed on a high-cholesterol diet.

@article{Yoshida2005EffectsOT,
  title={Effects of the cell wall of Kluyveromyces marxianus YIT 8292 on the plasma cholesterol and fecal sterol excretion in rats fed on a high-cholesterol diet.},
  author={Yasuto Yoshida and Wakae Yokoi and Kenji Ohishi and Masahiko Ito and Eiichiro Naito and Haruji Sawada},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2005},
  volume={69 4},
  pages={714-23}
}
The cellular components involved in the hypocholesterolemic activity of Kluyveromyces marxianus YIT 8292 were examined in rats fed on a high-cholesterol diet. Whole cells (KM) were heated at 115 degrees C for 10 minutes and fractionated into water-soluble extract 1 and the insoluble residue (KM-CW). After mechanical disruption by glass beads, KM-CW was separated into the cell wall (KM-W) and water-soluble extract 2. Plasma total cholesterol was decreased by feeding KM-CW or KM-W, but was not… CONTINUE READING

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