Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats

@article{Mansbach1996EffectsOT,
  title={Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats},
  author={Robert S. Mansbach and Charles C. Rovetti and Elaine Winston and John A. Lowe},
  journal={Psychopharmacology},
  year={1996},
  volume={124},
  pages={315-322}
}
SR141716A (Sanofi Recherche), a pyrazole derivative with high affinity for rat and human CB1 cannabinoid receptors, has recently been reported to reverse biochemical, physiological and behavioral effects induced by cannabinoid agonists. The present experiments characterized the activity of SR141716A (SR) in behavioral procedures designed to assess its antagonistic and intrinsic effects on unconditioned behavior and on complex learned behaviors. Six adult male pigeons were trained to… CONTINUE READING

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