Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats.

@article{Arulmani2004EffectsOT,
  title={Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats.},
  author={Udayasankar Arulmani and Martin P Schuijt and Jan P. C. Heiligers and Edwin W. Willems and Carlos M Villal{\'o}n and Pramod R. Saxena},
  journal={Basic & clinical pharmacology & toxicology},
  year={2004},
  volume={94 6},
  pages={291-7}
}
Several studies suggest that a calcitonin gene-related peptide (CGRP) receptor antagonist may have antimigraine properties, most probably via the inhibition of CGRP-induced cranial vasodilatation. We recently showed that the novel selective CGRP receptor antagonist, BIBN4096BS (1-piperidinecarboxamide, -N-[2-[[5-amino-1-[[4-(4-pyridinyl)-1-piperazinyl… CONTINUE READING