Effects of the angiotensin II type-1 receptor antagonist ZD7155 on angiotensin II-mediated regulation of renin secretion and renal renin gene expression, renal vasoconstriction, and blood pressure in rats.

Abstract

Angiotensin II receptors have recently been subclassified as type-1 or type-2 receptors. The in vitro and in vivo effects of blocking the angiotensin II type-1 receptor with ZD7155, an angiotensin II type-1 selective receptor antagonist, have been studied in angiotensin II-mediated increases in cytosolic calcium in rat mesangial cells, in angiotensin II… (More)

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@article{Krmer1998EffectsOT, title={Effects of the angiotensin II type-1 receptor antagonist ZD7155 on angiotensin II-mediated regulation of renin secretion and renal renin gene expression, renal vasoconstriction, and blood pressure in rats.}, author={B. K. Kr{\"a}mer and Theresia Ritthaler and Frank Schweda and Karl Peter Ittner and Hasso Scholz and G A J Riegger and Armin Kurtz}, journal={Journal of cardiovascular pharmacology}, year={1998}, volume={31 5}, pages={700-5} }