Effects of the administration of O2 on ventilation and blood gases in patients with chronic obstructive pulmonary disease during acute respiratory failure.

@article{Aubier1980EffectsOT,
  title={Effects of the administration of O2 on ventilation and blood gases in patients with chronic obstructive pulmonary disease during acute respiratory failure.},
  author={Michel Aubier and D Murciano and Joseph Milic-Emili and E Touaty and J Daghfous and Ren{\'e} Pariente and J. P. Derenne},
  journal={The American review of respiratory disease},
  year={1980},
  volume={122 5},
  pages={747-54}
}
The effects of the administration of 100% oxygen on minute ventilation (VE) and arterial blood gases were studied in patients with chronic obstructive pulmonary disease during acute respiratory failure. The administration of O2 resulted in an early decrease in VE, which averaged 18% +/- 2 SE of the control VE, and was due to a decrease in both tidal volume (VT) and respiratory frequency (f). This was followed by a slow increase in VE, such that after 15 min of breathing O2, VE rose to 93 +/- 6… CONTINUE READING

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