Effects of the Bacterial Extract OM-85 on Phagocyte Functions and the Stress Response

@article{Baladi1994EffectsOT,
  title={Effects of the Bacterial Extract OM-85 on Phagocyte Functions and the Stress Response},
  author={S. Baladi and Salom{\'e} Kantengwa and Y. R. A. Donati and Barbara S. Polla},
  journal={Mediators of Inflammation},
  year={1994},
  volume={3},
  pages={143 - 148}
}
The effects of the bacterial extract OM-85 on the respiratory burst, intracellular calcium and the stress response have been investigated in human peripheral blood monocytes from normal donors. Activation of the respiratory burst during bacterial phagocytosis has been previously associated with heat shock/stress proteins synthesis. Whereas OM-85 stimulated superoxide production and increased Ca(2+) mobilization, it fared to induce synthesis of classical HSPs. The lack of stress protein… CONTINUE READING