Effects of thalassemia major on bone mineral density in late adolescence.

@article{Benigno2003EffectsOT,
  title={Effects of thalassemia major on bone mineral density in late adolescence.},
  author={Vincenzo Benigno and Silvano Bertelloni and Giampiero Igli Baroncelli and Luca Bertacca and Salvatore Di Peri and Liana Cuccia and Zelia Borsellino and Maria Cristina Maggio},
  journal={Journal of pediatric endocrinology & metabolism : JPEM},
  year={2003},
  volume={16 Suppl 2},
  pages={337-42}
}
Management of thalassemia major has shown substantial clinical and prognostic improvement, suggesting the need for major attention to quality of life. We studied bone health in 25 patients (13 males, 12 females; 15-23 years old) affected by beta-thalassemia major. In all patients, bone mineral density (BMD), biochemical markers of bone and calcium metabolism (calcium, phosphate, magnesium, alkaline phosphatase, urinary calcium, 25-hydroxyvitamin D [25OH-D], 1,25-dihydroxyvitamin D [1,25(OH)2D… CONTINUE READING