Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbits.

@article{Liu2006EffectsOT,
  title={Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbits.},
  author={Ji-hong Liu and Jun Chen and Tao Wang and Bo Liu and Jun Yang and Xiao-Wen Chen and Shao-gang Wang and Chun-ping Yin and Zhang-qun Ye},
  journal={Asian journal of andrology},
  year={2006},
  volume={8 4},
  pages={
          405-9
        }
}
AIM To study the relaxation mechanisms of tetrandrine (Tet) on the corpus cavernosum smooth muscle. METHODS The corpus cavernosum smooth muscle cells from New Zealand white rabbits were cultured in vitro. [Ca(2+)](i) was measured by Fluorescence Ion Digital Imaging System, using Fluo-2/AM as a Ca(2+)-sensitive fluorescent indicator. RESULTS Tet (1, 10 and 100 micromol/L) had no effect on the resting [Ca(2+)](i) (P>0.05). In the presence of extracellular Ca(2+) (2.5 mmol/L), Tet (1, 10 and… CONTINUE READING

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