Effects of tetrahydropalmatine on post-traumatic stress disorder-induced changes in rat brain gene expression.

@article{Ceremuga2013EffectsOT,
  title={Effects of tetrahydropalmatine on post-traumatic stress disorder-induced changes in rat brain gene expression.},
  author={Tom{\'a}s Eduardo Ceremuga and P Shellabarger and Torbj{\"o}rn Persson and Margaret Fanning and Penny Galey and Daniel Robinson and Sabine Bertsch and George Allen Ceremuga and Michael Bentley},
  journal={Journal of integrative neuroscience},
  year={2013},
  volume={12 4},
  pages={513-28}
}
The aim of this research proposal was to investigate the effects of tetrahydropalmatine (THP) on gene expression in a post-traumatic stress disorder (PTSD) rodent model. Eighty male Sprague-Dawley rats were randomly assigned to the nonstressed groups or the 3-day restraint shock PTSD rodent model groups. There were four groups within the nonstressed rats (control, THP, midazolam, and midazolam with THP) and four groups within the stressed rats (control, THP, midazolam, and midazolam with THP… CONTINUE READING