Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men.

@article{Lu2006EffectsOT,
  title={Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men.},
  author={P. H. Lu and Donna A Masterman and Ruth A. Mulnard and Carl Cotman and Bruce Miller and Kristine Yaffe and Erin Reback and Verna Porter and Ronald S. Swerdloff and Jeffrey L. Cummings},
  journal={Archives of neurology},
  year={2006},
  volume={63 2},
  pages={177-85}
}
CONTEXT There is a compelling need for therapies that prevent, defer the onset, slow the progression, or improve the symptoms of Alzheimer disease (AD). OBJECTIVE To evaluate the effects of testosterone therapy on cognition, neuropsychiatric symptoms, and quality of life in male patients with mild AD and healthy elderly men. DESIGN Twenty-four-week, randomized, double-blind, placebo-controlled, parallel-group study. SETTING Memory disorders clinics as well as general neurology and… CONTINUE READING

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Testosterone prevents the heat shock-induced overactivation of glycogen synthase kinase-3 beta but not of cyclin-dependent (REPRINTED) ARCH NEUROL

  • S Papasozomenos, A. Shanavas
  • FEB 2006 WWW.ARCHNEUROL.COM
  • 2006
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