Effects of testosterone on antioxidant systems in male secondary hypogonadism.

  title={Effects of testosterone on antioxidant systems in male secondary hypogonadism.},
  author={Antonio Mancini and Erika Leone and Roberto Festa and G. C. Grande and Andrea Silvestrini and Laura de Marinis and Alfredo Pontecorvi and G Maira and Gian Paolo Littarru and Elisabetta Meucci},
  journal={Journal of andrology},
  volume={29 6},
Oxidative stress is involved both in metabolic syndrome and male infertility. Hypogonadism is also associated with increased risk for cardiovascular disease. To investigate the role of gonadal steroids in systemic antioxidant regulation, we determined plasma CoenzymeQ(10) (CoQ(10)) and total antioxidant capacity (TAC) in postsurgical hypopituitaric patients. Twenty-six patients aged 28-55 years were studied 6-12 months after surgery. CoQ(10) levels were measured by high-performance liquid… CONTINUE READING


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