Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data.

@article{Falutz2010EffectsOT,
  title={Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data.},
  author={J. Falutz and J. Mamputu and D. Potvin and G. Moyle and Graziella Soulban and H. Loughrey and C. Marsolais and R. Turner and S. Grinspoon},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 9},
  pages={
          4291-304
        }
}
CONTEXT HIV patients treated with antiretroviral therapy (ART) often develop increased visceral adipose tissue (VAT). OBJECTIVE Our objective was to perform a pooled analysis of two phase-3 studies of tesamorelin in ART-treated HIV patients with excess abdominal fat. DESIGN AND SETTING Two multicenter, international studies were conducted; a 26-wk randomized, placebo-controlled primary intervention phase was followed by a 26-wk safety extension. PATIENTS A total of 806 ART-treated HIV… Expand
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